Once you have the power broker,
you go after the mastermind behind them
ARACNe drew the map and VIPER caught the power broker on the scene; DIGGIT now tracks down the genomic alteration that was pulling that broker's strings. You learn how to stop at correlation no longer and join up the chain of causation — calculating it and checking it yourself instead of memorising formulas.
Python runs right inside this page. There is nothing to install.
How you'll learn
A regulon is the map of who knows whom, a master regulator is the power broker on the scene, a driver alteration is the mastermind behind them. Before you memorise the notation you get a picture of who moved whom.
Every piece of code has a run button. Mutual information, permutation tests — don't take anyone else's result on trust, compute them yourself.
Every lesson comes with an illustration of the idea it teaches.
You filter the candidates yourself, shake out the null distribution yourself, and combine the two lines of evidence yourself into the final leaderboard.